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  Peoplehavebeenwonderingwhyelephantsdonotdevelopcancereventhoughtheyhavelifespans(寿命)thataresimilartohumans,livingforaround50to70years.Nowscientistsbelievetheyknowwhy.AteamattheUniversityofChicago

  Peoplehavebeenwonderingwhyelephantsdonotdevelopcancereventhoughtheyhavelifespans(寿命)thataresimilartohumans,livingforaround50to70years.

  Nowscientistsbelievetheyknowwhy.AteamattheUniversityofChicago,UShasfoundthatelephantscarryalargenumberofgenesthatstoptumors(肿瘤)developing.Tobeprecise,theyfound20copiesofananti-tumorgenecalledTP53inelephants.Mostotherspecies,includinghumans,onlycarryonecopy.

  Accordingtotheresearch,theextracopiesofthegeneimprovedtheanimal'ssensitivitytoDNAdamage,whichletsthecellsquicklykillthemselveswhendamagedbeforetheycangoontoformdeadlytumors.

  "Anincreasedriskofdevelopingcancerhasstoodinthewayoftheevolutionoflargebodysizesinmanyanimals,"thestudyauthorDrVincentLynchtoldTheGuardian.Ifeverylivingcellhasthesamechanceofbecomingcancerous(癌变的),largecreatureswithalonglifespanlikewhalesandelephantsshouldhaveagreaterriskofdevelopingcancerthanhumansandmice.Butacrossspecies,theriskofcancerdoesnotshowaconnectionwithbodymass.

  ThisphenomenonwasfoundbyOxfordUniversityscientistRichardPetointhe1970sandlaternamed"Peto'sparadox(悖论)".Biologistsbelieveitresultsfromlargeranimalsusingprotectionthatmanysmalleranimalsdonot.Intheelephant'scase,themakingofTP53isnature'swayofkeepingthisspeciesalive.

  Thestudyalsofoundthatwhenthesamegeneswerebroughttolifeinmice,theyhadthesamecancerresistanceaselephants.Thismeansresearcherscouldusethediscoverytodevelopnewtreatmentsthatcanhelpstopcancersspreadingorevendevelopinginthefirstplace.

  "Naturehasalreadyfiguredouthowtopreventcancer,"saidJoshuaSchiffman,abiologistattheSchoolofMedicine,UniversityofUtah,US."It'suptoustolearnhowdifferentanimalsdealwiththeproblemsothatwecanusethosestrategiestopreventcancerinpeople."

  32.Whyareelephantsunlikelytodevelopcancer?___

  A.Theyhavearatherlargebodysize.

  B.TheirgenessuffernoDNAdamage.

  C.Certaingenesintheirbodykillexistingtumors.

  D.Theycarrymanygenestopreventtumorsde

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2019-11-04 12:41
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潘亚明

  32.D推理判断题.根据第二段AteamattheUniversityofChicago,UShasfoundthatelephantscarryalargenumberofgenesthatstoptumors(肿瘤)developing.可知在美国芝加哥大学的一个团队发现大象携带大量阻止肿瘤发展的基因.故选D.

  33.A推理判断题.根据第四段Anincreasedriskofdevelopingcancerhasstoodinthewayoftheevolutionoflargebodysizesinmanyanimals,可知在大体型的动物的进化中,患癌症的风险增加.由此可知,在进化中肿瘤是极大威胁.故选A.

  34.B词义猜测题.根据第四段Butacrossspecies,theriskofcancerdoesnotshowaconnectionwithbodymass.可知物种患癌症的几率和它们的体型没有关系.故选B.

  35.C主旨大意题.根据最后一段"It'suptoustolearnhowdifferentanimalsdealwiththeproblemsothatwecanusethosestrategiestopreventcancerinpeople."可知是时候了解不同的动物是如何处理这种问题,为了我们可以使用这些策略来预防癌症.而根据倒数第三段Intheelephant'scase,themakingofTP53isnature'swayofkeepingthisspeciesalive.可知在大象的案例中,TP53的制作是让这个物种存活的自然方法.由此推知,人们有望通过合成TP53来预防癌症.故选C.

2019-11-04 12:46:08

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